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With the current COVID-19 pandemic, evidence is mounting that a significant proportion of those who recover from COVID-19 have long-term impacts on many organs and systems. A few longitudinal studies on the long-term health impacts of COVID-19 have been published, although the follow-up was just one year after the initial infection. Our goal was to characterize the longitudinal evolution of health outcomes in hospital survivors with varying initial disease severity over the course of two years following acute COVID-19 infection, as well as to identify their recovery status. Long-term COVID symptoms were linked to lower quality of life, decreased exercise capacity, aberrant mental health, and increased health-care utilization after discharge. The findings suggest that further research into the path physiology of long COVID is required, as well as the development of effective therapies to lower the risk of long COVID.

To read the full paper, please download the linked file.