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Early Estimates of Bivalent mRNA Vaccine Effectiveness in Preventing COVID-19–Associated Hospitalization Among Immunocompetent Adults Aged ≥65 Years

29 Dec 2022

Over time, the monovalent COVID-19 mRNA vaccine-induced immunity deteriorates. All eligible individuals should receive a bivalent COVID-19 mRNA booster dosage, however nothing is known about how successful it is at preventing COVID-19 hospitalisation. A bivalent booster dose offered 73% more protection against COVID-19 hospitalisation among immunocompetent persons hospitalised in the multistate IVY Network than a previous monovalent mRNA vaccine alone did.

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CDC

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COVID-19
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